University of California, San Diego

Engineering Polyketide Synthases for Synthetic Chemistry: Engineered modular Type I PKSs have the potential to be an extraordinarily effective retrosynthesis platform for the bio-production of products from biofuels and commodity chemicals to both pharmaceutical and nonpharmaceutical fine and specialty chemicals, but this potential has only just begun to be realized as the compounds that have been made using engineered PKSs represent a small fraction of the potentially accessible chemical space. Speaker: Jay Keasling, Chief Executive Officer, Joint BioEnergy Institute | 7:09

DARPA Triage Challenge: Aims to drive breakthrough innovations in identification of “signatures” of injury that will help medical responders perform scalable, timely, and accurate triage. Speaker: BTO Program Manager Jean-Paul Chretien | 5:21

Russian Information Operations in Ukraine: Describes Russia's information operations campaign in the lead-up to and during the Ukraine invasion. Speaker: Jacob Shapiro, Special Advisor, Office of the Director of National Intelligence | 5:18

Quantum Computing: Discusses DARPA's current efforts to develop rigorous and quantitative methods for measuring progress and opportunity in the quantum computing space. Speakers: DSO Program Manager Joe Altepeter, DSO Director Jinendra Ranka. | 5:43

Future G in the DoD: Sets the stage for a discussion on the confluence of commercial and military communications focusing on the future of commercial cellular networks in the DoD including prior accomplishments, open challenges, and associated opportunities. Speaker: Tom Rondeau, Principal Director for 5G/Future G, Office of the Deputy Chief Technology Officer for Critical Technologies (DCTO(CT)) | 5:47

Using AI to Locate Critical Mineral Resources: Description. Speakers: DSO Program Manager Joshua Elliott; Graham Lederer, Research Geologist, US Geological Survey | 8:35

Mobile Force Protection (MFP): aims to address threats from small unmanned aircraft systems by developing scalable, modular, and affordable approaches that could be deployed in the next few years and nimbly evolve with advances in threats, tactics, and technology. Speaker: TTO Program Manager Gregory Avicola | 10:17

Extreme Optics and Imaging (EXTREME): Demonstrates a 10cm (~4in) planar metalens, which is a world record in size for a visible spectrum metalens. Speaker: DSO Program Manager Rohith Chandrasekar | 8:06

Atomic Magnetometer for Biological Imaging in Earth's Native Terrain (AMBIIENT): Demonstrates AMBIIENT technology to perform live magnetocardiography, the measurement of heart signals. This demonstrates the observation these faint magnetic signals outside of an expensive shielded room, in a typical environment. Speaker: MTO Program Manager Jonathan Hoffman. | 0:00

Ocean of Things: Demonstrates the observation these faint magnetic signals outside of an expensive shielded room, in a typical environment. Speaker: MTO Program Manager Jonathan Hoffman | 10:53

Thriving in Austere Environments: Provides a narrative of an expeditionary force and all the challenges and tools that are need to thrive in remote, austere environments. BTO Director Kerri Dugan | 31:25

Quantum: Separating the Real from the Hype: Separates the hype from the feasible and the real, with an emphasis on creating feasible real-world devices in the near-term and the prospects of near-term utility of quantum computing. Speaker: MTO Director Mark Rosker | 45:48

Bits to Bio: Discusses the future evolution of bio-sensing within the human body for information transfer, therapeutics, or performance enhancements. Moderators: BTO Program Manager Paul Sheehan, BTO Program Manager Benjamin Griffin. Panel: Marco Rolandi, Professor of Electrical and Computer Engineering, University of California, Santa Cruz; Giovanni Traverso, Assistant Professor, Department of Mechanical Engineering, Massachusetts Institute of Technology; Frederick Gregory, Branch Chief/Extramural Competency Co-Lead for Humans in Complex Systems, DEVCOM Army Research Laboratory. | 45:15

Expanding Operations in the Arctic: Arctic operations has become an increasing area of U.S. strategic concern due to Russia presence and China's economic interest. Access to the arctic is a challenge due to the lack of infrastructure and expansive area. U.S. interest in the arctic spans commerce, natural resources, freedom of navigation, situational awareness and homeland defense. Moderator: TTO Program Manager Kyle Woerner. Panel: MTO Program Manager David Abe; Matthew Dzieciuch, Researcher, Scripps Institute of Oceanography; Larry Mayer, Professor and Director of The Center for Coastal and Ocean Mapping at the University of New Hampshire. | 55:54

Software Development and Assurance Pipeline: Discusses the emerging software development pipeline model that is enabled by the automated capture and management of diverse kinds of engineering evidence, both formal and informal. Moderator: William Scherlis, Professor of Computer Science and Special Advisor to the Software Engineering Institute, Carnegie Mellon University; Natarajan Shankar, Distinguished Senior Scientist, Computer Science Laboratory, SRI International; Jeannette Wing, Executive Vice President for Research, Columbia University; Michael Hicks, Senior Principal Scientist, Amazon Web Services. | 46:03

Broadscale Innovations to Detect and Combat Disease: Presents an array of research breakthroughs is dealing with pathogens: detecting them in the air (bio/chemical weapons), combating their drug resistance and eradicating insect-borne diseases with the help of gene editing, and employing plant viruses as prefabricated nanoparticles in treatments of infectious diseases and cancer.

Panel (University of California, San Diego): Kim Prather, Distinguished Chair in Atmospheric Chemistry and Distinguished Professor, Scripps Institution of Oceanography and the Department of Chemistry and Biochemistry; Victor Nizet, Physician-Scientist and Distinguished Professor of Pediatrics and Pharmacy; Omar Akbari, Professor, Biological Sciences; Wei Xiong, Associate Professor, Department of Chemistry and Biochemistry; Nicole Steinmetz, Professor, NanoEngineering. | 37:47

Next Generation Communication: Communication is a central component of military operations and logistics. With ever-evolving hardware and software platforms, maintaining a competitive edge requires advanced interdisciplinary engagement and a spectrum of theoretical to applied work. Speaker: Sujit Dey, Professor, Electrical and Computer Engineering, University of California, San Diego. | 4:54