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Defense Advanced Research Projects AgencyAbout UsOfficesBiological Technologies Office

Biological Technologies Office (BTO)

BTO Hero Banner

DARPA’s Biological Technologies Office develops capabilities that embrace the unique properties of biology—adaptation, replication, complexity—and use these features to revolutionize how the United States prepares and protects its citizens, Soldiers, Sailors, Airmen, and Marines from threats at home and abroad. Example new Department of Defense capabilities include the ability to counter novel bioterrorism, deploy innovative biological countermeasures to protect its forces, and accelerate warfighter readiness/overmatch for adversary threats.

  • BTO Leadership, Program Managers, and Staff
  • Programs
  • Opportunities
  • BTO News Update - April 2018
To sign up for quarterly BTO News Updates, please e-mail darpabto@darpa.mil

Highlights

DARPA's Biological Technologies Office hosted the “Biotech Startups of the Future“ meeting September 13-14, 2017, at the Quadrus Center in Menlo Park, California.

BTO Lays Foundation for a New Generation of Biotech Ventures

Biotech is emerging as a breakthrough opportunity space that is ripe for fresh collaboration among DARPA, the nation's top researchers, venture capitalists, and entrepreneurs.
BTO Officewide

Innovation in Biotechnology

BTO’s “open” BAA offers a mechanism for researchers to reach DARPA with an idea that may fall outside of BTO’s current priorities, but that the proposer feels could be valuable to national security.
DARPA and the Brain Initiative

DARPA and the Brain Initiative

DARPA supports the Brain Initiative through a number of programs that are developing novel neurotechnologies, enabling new therapies, and advancing understanding of brain structure and function.

Tags

| Agency | Bio-complexity | Bio-systems | Disease | Health | Med-Devices | Syn-Bio |

 

Opportunities

To view a selective listing of solicitations posted by this office please visit the BTO Opportunities page, where you can further sort by topic.

Programs

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Advanced Plant Technologies (APT)

Dr. Blake Bextine
The Advanced Plant Technologies (APT) program seeks to develop plants capable of serving as next-generation, persistent, ground-based sensor technologies to protect deployed troops and the homeland by detecting and reporting on chemical, biological, radiological, nuclear, and explosive (CBRNE) threats. Such biological sensors would be effectively energy-independent, increasing their potential for wide distribution, while reducing risks associated with deployment and maintenance of traditional sensors. These technologies could also potentially support humanitarian operations by, for example, detecting unexploded ordnance in post-conflict settings. More
| Bio-complexity | Bio-systems | Sensors | Syn-Bio |

Autonomous Diagnostics to Enable Prevention and Therapeutics (ADEPT)

COL Matthew Hepburn, MD, USA
The Autonomous Diagnostics to Enable Prevention and Therapeutics (ADEPT) program supports individual troop readiness and total force health protection by developing technologies to rapidly identify and respond to threats posed by natural and engineered diseases and toxins. A subset of ADEPT technologies specifically support use by personnel with minimal medical training, delivering centralized laboratory capabilities even in the low-resource environments typical of many military operations. The program is part of a portfolio of DARPA-funded research aimed at providing options for preempting or mitigating constantly evolving infectious disease threats. More
| Disease | Health | Therapy |

Battlefield Medicine

Dr. Brad Ringeisen
The Battlefield Medicine program supports military readiness in far-forward deployed settings by overcoming logistical obstacles to manufacturing and delivery of urgently needed pharmaceutical products used to treat emerging threats. More
| Disease | Health | Therapy |

Biological Control

Dr. Paul Sheehan
The Biological Control program seeks to support a wide range of potential Department of Defense (DoD) applications by enhancing understanding of the basic processes associated with biological network interactions, communication, and control. Leveraging technologies developed under this program would enable construction of systems that seek out and mitigate chemical and biological threats; lead to the development of novel biomaterials that increase the resilience of Navy ships and other DoD systems to biofouling; and support military readiness by synthesizing new pharmaceuticals to treat emerging diseases. More
| Bio-complexity | Fundamentals | Math | Syn-Bio |

Biological Robustness in Complex Settings (BRICS)

Dr. Justin Gallivan
The Biological Robustness in Complex Settings (BRICS) program aims to transform engineered microbial biosystems into reliable, cost-effective strategic resources for the Department of Defense (DoD), enabling future applications in the areas of intelligence, readiness, and force protection. Examples include the identification of the geographical provenance of objects; protection of critical systems and infrastructure against corrosion, biofouling, and other damage; sensing of hazardous compounds; and efficient, on-demand bio-production of novel coatings, fuels, and drugs. More
| Bio-complexity | Bio-systems | Syn-Bio |
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Similarly    Tagged    Content

BTO Lays Foundation for a New Generation of Biotech Ventures
DARPA Launches Biological Technologies Office
Biological Technologies Office
Control Systems and Biology
Dr. Blake Bextine

Leadership

Dr. Justin Sanchez
Office Director
Dr. Brad Ringeisen
Deputy Director

Program Managers

Dr. Lori Adornato
Dr. Blake Bextine
Dr. Al Emondi
Dr. Justin Gallivan
COL Matthew Hepburn, MD, USA
Dr. Tristan McClure-Begley
Dr. Paul Sheehan
Dr. Eric Van Gieson
Dr. Renee Wegrzyn
ALL OFFICE STAFF
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Selected DARPA Achievements

DARPA collaborated with industry on stealth technology.
DARPA’s Stealth Revolution
In the early days of DARPA’s work on stealth technology, Have Blue, a prototype of what would become the F-117A, first flew successfully in 1977. The success of the F-117A program marked the beginning of the stealth revolution, which has had enormous benefits for national security.
DARPA microelectronics gave rise to today's GPS devices.
Navigation in the Palm of Your Hand
Early GPS receivers were bulky, heavy devices. In 1983, DARPA set out to miniaturize them, leading to a much broader adoption of GPS capability.
First rough conceptual design of the ARPANET.
Paving the Way to the Modern Internet
ARPA research played a central role in launching the Information Revolution. The agency developed and furthered much of the conceptual basis for the ARPANET—prototypical communications network launched nearly half a century ago—and invented the digital protocols that gave birth to the Internet.
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