Apr 8, 2025
Voices
- Leonard Tender, program manager, Biological Technologies Office
- Host: Stacey Wierzba, Public Affairs
Smart bandages, ocean-powered sensors, and quantum biology are innovations shaping the future of national security
What do smart bandages, ocean-powered sensors, and quantum biology have in common? They're all part of Leonard Tender's work at DARPA. Listen to Tender discuss his fascinating research in the Biological Technologies Office and how these innovations are shaping the future of national security.
Tender, a seasoned researcher with a background in electrochemistry and microbial research, joined DARPA in 2023 after a distinguished career at the Naval Research Laboratory. His expertise in understanding how microorganisms interact with electrical processes has led to groundbreaking advancements in wound care technology. Building on the success of the Bioelectronics for Tissue Regeneration (BETR) program, which focused on developing a "smart bandage" to monitor and accelerate wound healing, BTO is now embarking on a new initiative.
The Bioelectronics to Sense and Treat (BEST) program aims to create a closed-loop system that not only monitors wound healing in real-time but also actively treats infections. This advanced bandage will incorporate sensors to detect the presence of harmful microbes and analyze the host's immune response, tailoring treatment accordingly. This individualized approach is crucial, as immune responses can vary significantly depending on factors like stress, pre-existing conditions, and the battlefield environment. The program's ambitious three-year timeline includes independent development of monitoring and treatment capabilities, culminating in the integration of a closed-loop control system.
Beyond BEST, Tender's portfolio also encompasses innovative biomanufacturing and energy programs. These include converting waste plastics into useful materials like food and lubricants, and harnessing energy from the ocean using bioreactors inspired by filter-feeding marine animals. This diverse research reflects DARPA's commitment to exploring unconventional solutions to complex challenges.
Tender encourages researchers with groundbreaking ideas to connect with DARPA and contribute to the development of transformative technologies with far-reaching implications for national security and beyond. He describes his experience at DARPA as exhilarating and encourages others to consider joining the agency to pursue high-impact research.
Subscribe
