The Reliable Peripheral Interfaces (RPI) effort seeks to
demonstrate peripheral-nervous-system (PNS) interfaces that can reliably extract
motor-control information for intuitive control of high-performance upper-limb
prosthetics. This effort includes a variety of PNS-interface approaches such as
nerve cuffs, penetrating electrode arrays, regenerative interfaces,
tissue-engineered biological constructs, non-penetrating devices, invasive
electromyography (EMG) and sensory-input (stimulation) systems.
Technical Area #1: Create and demonstrate clinically viable
reliable-tissue interfaces to peripheral nerves and muscles.
Investments were made in the development of ultra-compliant probes
targeting the dorsal and ventral spinal nerve roots, miniature wireless
implantable EMG systems, a flat interface nerve electrode (FINE), regenerative
electrode technologies, and refinement of Utah slant electrode arrays (USEA)
resulting in first-in-human demonstrations. These peripheral
interfaces must enable stable, robust and high-channel count extensive recording
of limb-control-signal activity.
Technical Area #2:
Demonstrate the clinically viable tissue-interface electronics and packaging
necessary to enable the development and testing of reliable peripheral
interfaces designed to control many-DOF prosthetic limbs. Efforts
focused on implantable wireless systems for EMG recording and the high
performance electronic microsystems for epineural recording.
Area #3: Develop clinically viable algorithms and subsystems for
reliably decoding limb-control information from the detected peripheral signals.
Efforts in sparse PCA, Markov random fields, simultaneous decode of EMG,
beam-forming, time-delayed artificial neural nets, and creating motor neuron
pool models were launched.
Technical Area #4:
Demonstrate an advanced peripheral-interface system that can accurately
detect and decode peripheral limb-control signals in a manner that reliably
results in significant functional benefit. Human-use
demonstrations of military-relevant and high-DOF control of a prosthetic limb
using implantable EMG, surface EMG, and inter-neural recordings are
Technical Area #5: Demonstrate clinically
viable systems that provide tactile sensory and/or proprioceptive limb feedback
via stimulation of the peripheral nervous system. Reliable
stimulation of the peripheral nerves and dorsal root ganglion were
RPI is one of three complementary efforts within DARPA’s Reliable Neural-Interface Technology (RE-NET) program aimed at understanding why the performance of neural interfaces degrades over time and developing new high-performance neural interfaces that last the life of the patient.
You are now leaving the DARPA.mil website that is under the control and
management of DARPA. The appearance of hyperlinks does not constitute
endorsement by DARPA of non-U.S. Government sites or the information,
products, or services contained therein. Although DARPA may or may not
use these sites as additional distribution channels for Department of
Defense information, it does not exercise editorial control over all of
the information that you may find at these locations. Such links are
provided consistent with the stated purpose of this website.
After reading this message, click to continue