Defense Advanced Research Projects AgencyWork With UsOpportunities


Established in 1958 as part of the U.S. Department of Defense, DARPA pursues opportunities for transformational change rather than incremental advances. It does so collaboratively as part of a robust innovation ecosystem that includes academic, corporate, and governmental partners. To fulfill its mission, the Agency relies on diverse performers from throughout this ecosystem to apply multi-disciplinary approaches to both advance knowledge through basic research and create innovative technologies that address current and predicted practical problems through applied research. The list of selected opportunities displayed below is provided for convenience. For a complete listing of DARPA opportunities please visit the FedBizOpps website. More

In addition to program-specific opportunities, each DARPA technical office maintains an “office-wide” Broad Agency Announcement (BAA) that covers a range of technical areas of interest to each particular office. The office-wide BAAs are refreshed on an annual basis and offer a mechanism for researchers to reach DARPA with ideas that they feel could be valuable to national security.


Response date: 4/26/2018
Biological Technologies Office-wide Broad Agency Announcement
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative research proposals of interest to the Biological Technologies Office (BTO). Proposed research should investigate leading edge approaches that enable revolutionary advances in science, technologies, or systems at the intersection of biology with engineering and the physical and computer sciences. Specifically excluded is research that primarily results in evolutionary improvements to the existing state of the art. BTO seeks unconventional approaches that are outside the mainstream, challenge assumptions, and have the potential to radically change established practice, lead to extraordinary outcomes, and create entirely new fields.
Response date: 4/25/2018
Friend or Foe
The Friend or Foe (FoF) program will develop the capability to rapidly identify potential bacterial pathogens in complex environments through analysis of their behavior (i.e., their phenotype). New pathogens, both naturally occurring and adversary-engineered, are increasingly likely to emerge due to changes in the environment, rising global population, and the wide availability of genetic engineering tools to both state and non-state actors.
Response date: 4/30/2018
Persistent Aquatic Living Sensors (PALS)
DARPA seeks innovative proposals for new systems that employ natural or engineered marine organisms as sensor elements to amplify signals related to the presence, movement, and classification of manned or unmanned underwater vehicles (M/UUV). The Persistent Aquatic Living Sensors (PALS) program will leverage or develop living organisms as sensor transducers, and pair them with a detector and analysis suite to produce deployable sensor systems able to provide timely information on vehicle activity across a wide variety of maritime environments.
Response date: 5/3/2018
Epigenetic CHaracterization and Observation (ECHO)
The Epigenetic CHaracterization and Observation (ECHO) program will utilize an individual's epigenome to reveal their history of exposure to weapons of mass destruction (WMD) and WMD precursors. The program will build a field-deployable platform capable of using the epigenome to diagnose biothreat exposures and infections and support military forensics operations to counter-WMD proliferation.
Response date: 5/22/2018
DARPA seeks novel approaches to reversibly pause and/or slow the functions and preserve viability of living cells without reliance on cold temperature. This new technology aims to directly address needs within the Department of Defense to maintain and deliver biological therapeutics and extend the window of time for effective use of field forward therapeutics.