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Defense Advanced Research Projects AgencyAbout UsOfficesBiological Technologies Office

Biological Technologies Office (BTO)

BTO Hero Banner

DARPA’s Biological Technologies Office develops capabilities that embrace the unique properties of biology—adaptation, replication, complexity—and applies those features to revolutionize how the United States defends the homeland and prepares and protects its Soldiers, Sailors, Airmen, and Marines. BTO is helping the Department of Defense to counter novel forms of bioterrorism, deploy innovative biological countermeasures to protect U.S. forces, and accelerate warfighter readiness and overmatch to confront adversary threats.

  • BTO Leadership, Program Managers, and Staff
  • BTO Capability Areas
          Detect and characterize any threat, any time, anywhere
          Enable rapid, scalable protection and countermeasures
          Revolutionize warfighter readiness, resilience, and recovery
          Enhance training effectiveness and overmatch
          Develop non-traditional platforms and capabilities
  • Programs
  • Opportunities
  • BTO News Update - April 2018
  • To sign up for BTO News Updates, please e-mail darpabto@darpa.mil

Highlights

DARPA's Biological Technologies Office hosted the “Biotech Startups of the Future“ meeting September 13-14, 2017, at the Quadrus Center in Menlo Park, California.

BTO Lays Foundation for a New Generation of Biotech Ventures

Biotech is emerging as a breakthrough opportunity space that is ripe for fresh collaboration among DARPA, the nation's top researchers, venture capitalists, and entrepreneurs.
BTO Officewide

Innovation in Biotechnology

BTO’s “open” BAA offers a mechanism for researchers to reach DARPA with an idea that may fall outside of BTO’s current priorities, but that the proposer feels could be valuable to national security.
DARPA and the Brain Initiative

DARPA and the Brain Initiative

DARPA supports the Brain Initiative through a number of programs that are developing novel neurotechnologies, enabling new therapies, and advancing understanding of brain structure and function.

Tags

| Agency | Bio-complexity | Bio-systems | Disease | Health | Med-Devices | Syn-Bio |

 

Opportunities

To view a selective listing of solicitations posted by this office please visit the BTO Opportunities page, where you can further sort by topic.

Programs

Collapse List     View 10 | View 50 | View All

Restoring Active Memory (RAM)

Dr. Tristan McClure-Begley
The Restoring Active Memory (RAM) program aims to mitigate the effects of traumatic brain injury (TBI) in military Service members by developing neurotechnologies to facilitate memory formation and recall in the injured brain. More than 270,000 Service members have been diagnosed with TBI since 20001. The condition frequently results in an impaired ability to retrieve memories formed prior to injury and a reduced capacity to form or retain new memories following injury. Despite the scale of the problem, few effective therapies currently exist to mitigate the long-term consequences of TBI on memory. Enabling restoration of memory function would support military readiness by providing injured personnel the option of returning to duty, and would improve quality of life for wounded veterans. More
| Health | Med-Devices | Neuroscience | Restoration | Training |

ReVector

Dr. Christian Sund
Mosquitoes transmit pathogens that cause dengue, malaria, and other diseases that present significant risks to the readiness and resilience of military personnel, and public health more generally. The ReVector program aims to maintain the health of military personnel operating in disease-endemic regions by reducing attraction and feeding by mosquitoes. More
| Disease | Health | Therapy |

Revolutionizing Prosthetics

Dr. Al Emondi
Thanks to improvements in body armor and combat casualty care, military Service members are now surviving severe battlefield injuries that involve traumatic limb amputation. However, because these survivors are predominantly young, they must live with their injuries for decades. This severely diminishes affected individuals’ quality of life and places a massive responsibility on the military's medical and rehabilitation system. More
| Health | Med-Devices | Neuroscience | Restoration |

Safe Genes

Dr. Renee Wegrzyn
The Safe Genes program supports force protection and military health and readiness by protecting Service members from accidental or intentional misuse of genome editing technologies. Additional work will leverage advances in gene editing technology to expedite development of advanced prophylactic and therapeutic treatments against gene editors. Advances within the program will ensure the United States remains at the vanguard of the broadly accessible and rapidly progressing field of genome editing. More
| Bio-complexity | Bio-systems | Countermeasures | Syn-Bio |

Systems-Based Neurotechnology for Emerging Therapies (SUBNETS)

Dr. Al Emondi
The Systems-Based Neurotechnology for Emerging Therapies (SUBNETS) program aims to improve force health by using neurotechnology as the basis for effective, informed, and precise treatments for neuropsychiatric illnesses in military Service members. The effects of such illnesses, brought on by war, traumatic injuries, and other experiences, remain challenging to treat. Current treatment approaches—surgery, medications, and psychotherapy—can often help to alleviate the worst effects of illnesses such as major depression and post-traumatic stress, but they are imprecise and not universally effective. Through SUBNETS, DARPA seeks to generate the knowledge and technology required to deliver relief to patients with otherwise intractable neuropsychiatric illness. More
| Health | Med-Devices | Neuroscience | Therapy |
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Detect and characterize any threat, any time, anywhere
Biological Technologies
Detect It with Gene Editing Technologies (DIGET) Proposers Day
PReemptive Expression of Protective Alleles and Response Elements (PREPARE) Proposers Day
Gene Editors Could Find New Use as Rapid Detectors of Pathogenic Threats

Leadership

Dr. Brad Ringeisen
Office Director
Dr. Kerri Dugan
Deputy Director

Program Managers

Dr. Lori Adornato
Dr. Blake Bextine
Dr. Rohit Chitale
Dr. Seth Cohen
Dr. Al Emondi
Dr. Amy Jenkins
Dr. Tristan McClure-Begley
Dr. Paul Sheehan
Dr. Christian Sund
Dr. Eric Van Gieson
Dr. Renee Wegrzyn
ALL OFFICE STAFF
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Selected DARPA Achievements

DARPA collaborated with industry on stealth technology.
DARPA’s Stealth Revolution
In the early days of DARPA’s work on stealth technology, Have Blue, a prototype of what would become the F-117A, first flew successfully in 1977. The success of the F-117A program marked the beginning of the stealth revolution, which has had enormous benefits for national security.
DARPA microelectronics gave rise to today's GPS devices.
Navigation in the Palm of Your Hand
Early GPS receivers were bulky, heavy devices. In 1983, DARPA set out to miniaturize them, leading to a much broader adoption of GPS capability.
First rough conceptual design of the ARPANET.
Paving the Way to the Modern Internet
ARPA research played a central role in launching the Information Revolution. The agency developed and furthered much of the conceptual basis for the ARPANET—prototypical communications network launched nearly half a century ago—and invented the digital protocols that gave birth to the Internet.
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