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DARPA’s Biological Technologies Office develops capabilities that embrace the unique properties of biology—adaptation, replication, complexity—and applies those features to revolutionize how the United States defends the homeland and prepares and protects its Soldiers, Sailors, Airmen, and Marines. BTO is helping the Department of Defense expand technology-driven capabilities to detect novel threats and protect U.S. force readiness, deploy physiological interventions to maintain operational advantage, support warfighter performance, and focus on operational biotechnology for mission success.