Defense Advanced Research Projects AgencyTagged Content List

Prevention and Therapy

Biomedical technologies designed to thwart initial infection or injury, or enable faster healing afterward

Showing 60 results for Therapy RSS
The Dialysis-Like Therapeutics (DLT) program aims to support force protection and military readiness by improving critical care in low-resource environments and delivering a new tool for rapid response to emerging infectious disease threats. DLT specifically addresses a life-threatening blood infection known as sepsis, but DARPA is working to expand the DLT technology to also mitigate threats from harmful bacteria, viruses, fungi, and toxic agents in the blood.
Military service members experience an increased lifetime risk of neuropsychiatric conditions, such as depression, post-traumatic stress, and substance abuse. These conditions are substantially more prevalent in both the active duty population and veterans relative to civilians.
With a focus on wounded warriors and facilitating their return to military service, the Hand Proprioception and Touch Interfaces (HAPTIX) program is pursuing key technologies to enable precision control of and sensory feedback from sensor-equipped upper-limb prosthetic devices. If successful, the resulting system would provide users near-natural control of prosthetic hands and arms via bi-directional peripheral nerve implants. The program has a strong focus on technology handoff and aims to create and transition clinically relevant technology in support of wounded warriors suffering from single or multiple limb loss.
Microbial infections are a problem of particular concern to the Department of Defense (DoD). The DoD has long recognized the warfighter’s outsized risk of exposure to infectious disease, including the rise of antimicrobial resistant (AMR) and multidrug resistant (MDR) pathogens that have challenged military wound care in Iraq and Afghanistan. Furthermore, the responsibility of the DoD to protect the homeland encompasses biological threat agents, including bacterial threats, for which effective countermeasures are critical.
The In Vivo Nanoplatforms (IVN) program supports military readiness through the development of in vivo sensing technologies and therapeutics that facilitate optimal health and performance in individual warfighters. The program pursues technologies that provide early indication of physiological abnormalities or illness that can be proactively addressed with therapeutics or supportive care.