Defense Advanced Research Projects AgencyTagged Content List

Apply Biological Complexity at Scale

Relating to insights that can be derived from examining living-system dynamics at an enormous range of spatial, physical and temporal scales

Showing 12 results for Bio-complexity + Countermeasures RSS
10/15/2019
DARPA launched the Safe Genes program in 2017 to establish a “safety by design” strategy for guiding the development of an array of powerful, emergent genome editing technologies. Consistent with the National Biodefense Strategy published last year, DARPA’s goals for Safe Genes are to mitigate the risks and security concerns related to the accidental or intentional misuse of such technologies and, at the same time, enable the pursuit of novel genetic solutions that support public health and military force protection and readiness.
November 18, 2016,
Executive Conference Center / Webinar
DARPA’s Biological Technologies Office is hosting a Proposers Day meeting to provide information to potential applicants on the structure and objectives of the new Insect Allies program. Insect Allies will seek to develop vector-mediated modification technologies for mature plants to rapidly counter environmental and biological threats to crops. DARPA believes that the high specificity of genetic modification coupled with quick plant gene uptake could allow crops to be protected from threats within a single growing season.
June 13, 2018,
Westin Arlington Gateway Hotel
DARPA’s Biological Technologies Office is hosting a Proposers Day meeting to provide information to potential applicants on the structure and objectives of the new PReemptive Expression of Protective Alleles and Response Elements (PREPARE) program. PREPARE will explore ways to better protect against biological, chemical, or radiological threats by temporarily and reversibly tuning gene expression to bolster the body’s defenses against—or directly neutralize—a given threat. It will focus on four key health challenges as proofs of concept: influenza viral infection, opioid overdose, organophosphate poisoning, and exposure to gamma radiation.
September 30, 2016,
United States Institute of Peace
DARPA’s Biological Technologies Office (BTO) is hosting a Proposers Day to provide information to potential proposers on the objectives of the upcoming Safe Genes program. The program aims to help unlock the potential of advanced gene editing technologies by developing a set of biosafety and biosecurity tools to address potential risks of this rapidly advancing field.
The Insect Allies program is pursuing scalable, readily deployable, and generalizable countermeasures against potential natural and engineered threats to the food supply with the goals of preserving the U.S. crop system. National security can be quickly jeopardized by naturally occurring threats to the crop system, including pathogens, drought, flooding, and frost, but especially by threats introduced by state or non-state actors. Insect Allies seeks to mitigate the impact of these incursions by applying targeted therapies to mature plants with effects that are expressed at relevant timescales—namely, within a single growing season.