Defense Advanced Research Projects AgencyTagged Content List

Injury and Trauma

Relating to diagnosis and treatment of grievous physical and mental injury

Showing 20 results for Injury RSS
Previous efforts to understand brain injuries that result from nonkinetic explosive effects have focused only on a single explanation—blast overpressure. Improvised explosive device (IED)-induced injuries in Iraq, however, do not fit this hypothesis. Evidence indicates that traumatic brain injuries unique to blast exposure do not exhibit typical overpressure injuries, such as damage to gas-filled organs like lungs and bowel. DARPA’s Preventing Violent Explosive Neurologic Trauma (PREVENT) program is comprehensively evaluating the physics of the interaction between an IED blast and the brain and has identified which blast components are associated with neurologic injury.
The Reorganization and Plasticity to Accelerate Injury Recovery (REPAIR) program aims to uncover the mechanisms underlying neural computation and reorganization to improve modeling of the brain and our ability to interface with it.
The Surviving Blood Loss (SBL) program is developing novel strategies to radically extend the time injured warfighters can survive critical blood loss on the battlefield before initiation of fluid and blood resuscitation. Achieving this goal will allow increased time—as much as hours or days—for evacuation, triage, and initiation of supportive therapies.
Uncontrolled blood loss is the leading cause of death for warfighters on the battlefield, according to the U.S. Army Institute of Surgical Research. The vast majority of such fatalities are from wounds that are not accessible by combat medics for traditional treatments, like direct compression. For example, in the case of internal injuries to the abdominal cavity, medics can neither visualize the damage nor access it to provide treatment. As a result, rapid and uncontrolled blood loss often leads to death before transport from the battlefield to a surgical setting can occur.
This announcement seeks revolutionary research ideas for topics not being addressed by ongoing BTO programs or other published solicitations.