Defense Advanced Research Projects AgencyTagged Content List

Injury and Trauma

Relating to diagnosis and treatment of grievous physical and mental injury

Showing 18 results for Injury RSS
The Surviving Blood Loss (SBL) program is developing novel strategies to radically extend the time injured warfighters can survive critical blood loss on the battlefield before initiation of fluid and blood resuscitation. Achieving this goal will allow increased time—as much as hours or days—for evacuation, triage, and initiation of supportive therapies.
Uncontrolled blood loss is the leading cause of death for warfighters on the battlefield, according to the U.S. Army Institute of Surgical Research. The vast majority of such fatalities are from wounds that are not accessible by combat medics for traditional treatments, like direct compression. For example, in the case of internal injuries to the abdominal cavity, medics can neither visualize the damage nor access it to provide treatment. As a result, rapid and uncontrolled blood loss often leads to death before transport from the battlefield to a surgical setting can occur.
10/29/2019
Military service members and veterans face serious occupational trauma; one element in particular relates to the significantly increased risk of acute and chronic neuropsychiatric conditions. Neuropsychiatric conditions in the military are particularly impactful because options for treating them are limited. No therapy currently exists that can deliver rapid relief of neuropsychiatric symptoms and is reasonable for use in a broad spectrum of conditions. Neuropsychiatric conditions are complex, and presentation is highly subject to significant inter-individual variability. Focused Pharma aims to develop new drugs that target specific neurotransmitter receptor signaling modes to deliver near immediate relief that is generalizable across indications and individuals.