Defense Advanced Research Projects AgencyTagged Content List

Injury and Trauma

Relating to diagnosis and treatment of grievous physical and mental injury

Showing 18 results for Injury RSS
11/28/2018
Flying at 50,000 feet, diving deep in the ocean, or hiking for miles with gear through extreme climates, military service members face conditions that place unique burdens on their individual physiology. The potential exists to develop pharmacological interventions to help service members complete their toughest missions more safely and efficiently, and then recover more quickly and without adverse effects, but those interventions must work on complex physiological systems in the human body.
02/06/2019
Blast injuries, burns, and other wounds experienced by warfighters often catastrophically damage their bones, skin, and nerves, resulting in months to years of recovery for the most severe injuries and often returning imperfect results. This long and limited healing process means prolonged pain and hardship for the patient, and a drop in readiness for the military. However, DARPA believes that recent advances in biosensors, actuators, and artificial intelligence could be extended and integrated to dramatically improve tissue regeneration. To achieve this, the new Bioelectronics for Tissue Regeneration (BETR) program asks researchers to develop bioelectronics that closely track the progress of the wound and then stimulate healing processes in real time to optimize tissue repair and regeneration.
December 14, 2018, 10:00 AM ET,
Executive Conference Center
The Biological Technologies Office is holding a Proposers Day to provide information on the structure and objectives of the Panacea program. Panacea aims to integrate systems pharmacology and advanced medicinal chemistry approaches to expand the human drug target space for therapeutic interventions in the areas of acute management of pain and inflammation and the improvement of physiological endurance under oxygen-limited conditions or environments. Panacea will support the development and proof-of-concept demonstration of a new integrated platform for the rapid prediction, synthesis, and validation of pharmacological interventions.
The Bioelectronics for Tissue Regeneration (BETR) program will develop technology aimed at speeding warfighter recovery, and thus resilience, by directly intervening in wound healing. To do this, researchers will build an adaptive system that uses actuators to biochemically or biophysically stimulate tissue, sensors to track the body’s complex response to that stimulation, and adaptive learning algorithms to integrate sensor data and dictate intervention to the actuators.
The Biostasis program aims to extend the time for lifesaving medical treatment, often referred to as “the Golden Hour,” following traumatic injury or acute infection, thus increasing survivability for military personnel operating in far-forward conditions with limited access to medical professionals or trauma centers. To do so, Biostasis is developing novel chemical biology approaches that reversibly and controllably slow biological systems without cold-chain to stabilize and protect their functional capacity until medical intervention is possible.