Defense Advanced Research Projects AgencyTagged Content List

Infectious Disease

Relating to ailments caused by pathogens

Showing 20 results for Disease + News RSS
05/08/2013
For more than fifty years, researchers have been studying exactly how aspirin affects the human body. Despite thousands of publications on the topic, our understanding is still incomplete.
08/14/2014
The Chikungunya virus (CHIKV) is on the move. Spread among humans by mosquitoes, and spread across geographic boundaries by humans who travel, the virus—which causes a debilitating illness—is now expanding through the Western Hemisphere. Governments and health organizations could take proactive steps to limit its spread if they had accurate forecasts of where and when it would appear. DARPA’s CHIKV Challenge asks teams to create models to deliver such forecasts for all of the countries and territories in the Americas and the Caribbean over a six-month period starting in September 2014.
08/26/2014
The body’s peripheral nervous system constantly monitors the status of internal organs and helps regulate biological responses to infection, injury or other imbalances. When this regulatory process goes awry due to injury or illness, peripheral nerve signals can actually exacerbate a condition, causing pain, inflammation or immune dysfunction.
09/15/2014
Sepsis—a life-threatening over-reaction by the immune system to infection—afflicts 18 million people a year worldwide and kills between 30 and 50 percent of them. Sepsis poses a significant threat to warfighters who suffer combat injuries that predispose them to infection. Antibiotics can kill sepsis-inducing microbes but their overuse is contributing to the threat of drug-resistant microbes and they don’t neutralize the toxins that some pathogens leave behind. Commercial dialysis equipment can remove toxins from the blood but is not built for routine use in theater.
11/06/2014
Many businesses and academic researchers wishing to pursue cutting-edge research ideas with government support lack the resources to navigate the burdensome paperwork requirements required to win federal grants or contracts. DARPA’s Biological Technologies Office (BTO) has created a simplified proposal process to attract and fund new ideas from just those types of innovators—those operating at the intersection of biology and technology who may never have worked with the Defense Department and may otherwise have remained too daunted to try.