Defense Advanced Research Projects AgencyTagged Content List

Infectious Disease

Relating to ailments caused by pathogens

Showing 44 results for Disease RSS
DARPA’s Biological Technologies Office develops capabilities that embrace the unique properties of biology—adaptation, replication, complexity—and use these features to revolutionize how the United States prepares and protects its citizens, Soldiers, Sailors, Airmen, and Marines from threats at home and abroad. Example new Department of Defense capabilities include the ability to counter novel bioterrorism, deploy innovative biological countermeasures to protect its forces, and accelerate warfighter readiness/overmatch for adversary threats.
To accelerate the development of new infectious disease forecasting methods, DARPA launched its CHIKV Challenge. The chikungunya virus (CHIKV) first appeared in the Americas in 2013 but was quickly spreading and by mid-2015, the Pan-American Health Organization (PAHO) had tallied close to 1.4 million suspected cases and more than 33,000 confirmed. Spread by mosquitoes, chikungunya is rarely fatal but can cause debilitating joint and muscle pain, fever, nausea, fatigue, and rash, and poses a growing public health and national security risk.
For more than fifty years, researchers have been studying exactly how aspirin affects the human body. Despite thousands of publications on the topic, our understanding is still incomplete.
The Chikungunya virus (CHIKV) is on the move. Spread among humans by mosquitoes, and spread across geographic boundaries by humans who travel, the virus—which causes a debilitating illness—is now expanding through the Western Hemisphere. Governments and health organizations could take proactive steps to limit its spread if they had accurate forecasts of where and when it would appear. DARPA’s CHIKV Challenge asks teams to create models to deliver such forecasts for all of the countries and territories in the Americas and the Caribbean over a six-month period starting in September 2014.
The body’s peripheral nervous system constantly monitors the status of internal organs and helps regulate biological responses to infection, injury or other imbalances. When this regulatory process goes awry due to injury or illness, peripheral nerve signals can actually exacerbate a condition, causing pain, inflammation or immune dysfunction.