Defense Advanced Research Projects AgencyTagged Content List


The identification and transformation of substances

Showing 19 results for Chemistry + Fundamentals RSS
Efficient discovery and production of new molecules is essential to realize capabilities across the DoD, from simulants and medicines essential to counter emerging threats, to coatings, dyes and specialty fuels needed for advanced performance.
Destroying bulk stores of chemical warfare agents (CWAs) and organic precursors is a significant challenge for the international community. Today, for example, there are no approaches that exploit chemistries that are truly agnostic in terms of the agents that can be processed. In addition, current approaches require transport of agents from the storage site to a neutralization site. Ensuring safe transport of the agent can add significant cost and time to the process.
Health threats often evolve more quickly than health solutions. Despite ongoing research in the government and the biopharmaceutical industry to identify new therapies, the Department of Defense (DoD) currently lacks tools to address the full spectrum of chemical, biological, and disease threats that could impact the readiness of U.S. forces.
Coatings, thin films and advanced surfaces are important aspects of systems, devices and technologies critical to the mission of the Department of Defense. Despite decades of work, methods that enable atomic through millimeter-scale control over structure and properties of materials deposited on surfaces are still underdeveloped. For example, structural organization of high-value thin films is typically controlled by high-temperature deposition or annealing, but the temperatures employed during thin-film synthesis and deposition exceed the limits of many DoD-relevant substrates, restricting application opportunities.
Synthetic chemistry is important across countless technological areas, from medicines to energetics to advanced coatings to functional materials. While our synthetic capabilities have developed rapidly over the last century, current approaches are still slow and inefficient, with poor reproducibility and scalability and limited use of prior knowledge. Such an approach not only limits production of known materials, but also impedes discovery of better synthetic routes and completely new molecules.